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Virion Biotherapeutics Strategic Analysis

Prudence K. Magezi
Latest posts by Prudence K. Magezi(see all)

    Today, chronic diseases are among the most prevalent and costly health conditions in the United States and the world over. According to research, at least 45% (133 million) of all Americans suffer from at least one chronicle disease and this number continues to grow (Raghupathi and Raghupathie 2018). 
    It is thus no surprise that the biologics industry is growing very fast, surpassing the growth of small molecule tablets. According to research, the global biologics contract development and manufacturing organization (CDMO) market, valued at $9.93 billion in 2020, is expected to reach $18.90 billion by 2026, recording a CAGR of 11.2% between 2021 and 2026.  
    Despite the popularity of small-molecule drugs globally, large molecules, such as biologics, biosimilars as well as cell and gene therapies, are forecast to witness the strongest growth between 2021 and 2026. The large molecule market which includes originator biologics, biologics, cells, and gene therapies will reach $133 billion by 2023.  Monoclonal antibodies (mAbs) and their counterparts (biosimilars) have in recent years attracted a notable amount of investment in the biologics industry mainly due to their proven success in treating various chronic diseases, including cancer.  
    Virion Therapeutics LLC is one of the companies that have continued to gain recognition in the field of therapeutics. Today, the company is involved in the production of VRON-0200, a Therapeutic Vaccine for Chronic Hepatitis B Virus.  In the USA, at least 862,000 people were chronically infected with HBV in 2016.
    With this and many other chronic diseases on the rise globally, there are many opportunities for Virion because of its ability to produce treatments for chronic viral infections utilizing the first genetically encoded checkpoint inhibitor given via vaccination.

    The report analyzes the major strategic issues and challenges facing Virion Therapeutics including high costs, long approval times, uncertainty of long-term demand, and supply chain issues likely to impact the growth of Virion Therapeutics despite the growing demand for biologics. 

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    CHICAGO
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    Coursework assessment (4000 words)

    Choose one of the following organizations and develop an appropriate area for structured investigation/design/ development; 

    • Cote Restaurants Ltd
    • Clarion Events
    • Worldremit
    • Virion Biotherapeutics Ltd
    • Ace Cultural Tours Ltd
    • Four Seasons Health Care
    • AGE UK

    The four stages of your research project must incorporate;

    • Writing a report of 4,000 words with four key components: 1) strategic analysis of external, 2) internal, 3) competitive, and 4) practice factors 
    • Assessment of challenges derived from that strategic analysis 
    • Development of solutions to those challenges you have identified
    • Implementation of one of those solutions 

     


    Key Learning Outcomes

    By the end of this assignment, students should be able to:

    • Define a challenge to allow the development of steps to meet it. 
    • Collect, organize, understand, and interpret information from a variety of appropriate resources, acting autonomously, with minimal supervision; 
    • Identify, select, and justify the use of appropriate techniques, methods, and development strategies; 
    • Critically evaluate evidence to justify and support conclusions/recommendations;  

     

    INTRODUCTION


    Virion Therapeutics, LLC is a science-driven organization that deals in the development of innovative immune-based treatments meant for cancers and other chronic viral infections that use genetically encoded checkpoint inhibitor that is given through vaccination. Founded in 2018, Virion is a leader in biomedical research, an expert in cancer and infectious diseases research, equipped with far-reaching domain knowledge in the oncology biotherapeutic field, vaccines, and antivirals (Bloomberg 2021).

    Biotherapeutics has especially been the fastest-growing sector in the pharmaceutical industry, with an annual growth of over 8%. As of 2020, industry revenue reached USD $325.17 billion, a very fast growth considering that it was worth $163 billion in 2017. This growth has been boosted by the safety and effectiveness of company products as well as their ability to treat diseases that were historically considered incurable 

    With total funding of $14.1 million, the company has continued to gain recognition in the field through its innovations. As of 2021, Virion Therapeutics LLC was working on developing VRON-0200, a therapeutic vaccine for chronic HBV infections. According to research, the vaccine uses key HBV antigens that are conserved between several viral genotypes and joined with an innovative genetically encoded inhibitor of an early T cell checkpoint that blunts T cell activation and prevents damage to the liver (Virion Therapeutics 2021). 

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